PhDone!

August 18, 2021

Major life update: I successfully defended my thesis and earned my doctorate in toxicology from the University of Rochester. PhDistance is official now!

The leadup to the defense felt protracted, but not very stressful. I must have practiced my talk over ten times, so I felt prepared and genuinely excited to give a talk to my friends, family, colleagues, and committee.

About ten minutes before my defense, I logged on to Zoom to ensure everything was working correctly, like the Share Screen feature. Oh, by the way, I defended my thesis via Zoom due to the pandemic. Sure, it’s not how I dreamt I would end my PhD, but given the fact that I live in North Carolina now, it was very convenient.

After a very sweet introduction by my advisor (complete with photos of me and handmade cards I had made for him over the years) I began my talk. My friend, Kelly, took screen-shots of me during it:

Methylmercury is released by industrial activities (e.g., coal-fired power plants) and natural sources and cycles through the environment
Biomarker data from national biomonitoring programs showing levels of blood mercury by country. Pregnant women are advised to limit consumption of SOME fish because methylmercury is found in fish and is bad for babies brain development.
The Faroe Island’s and Seychelle Islands are the locations of two ongoing longitudinal cohort studies evaluating exposure to methylmercury during development and adverse outcomes in children as they age.

About 45 minutes later, I was done talking about research and began my photo collage of acknowledgements:

That’s all, folks! Also, I’m about to cry…
My advisor!
My lab-mate, neighbor, best-friend, and fellow Drosoph-a-teer, Jakob!
Thanks, guys!
My lovely running buddies! Erin is another PhDistance gal.

I got a chance to answer a few good questions after the photo sharing. Then, I logged into another Zoom link for my closed-door defense. Whereas the open-door defense is public and involves me filling the hour with a research talk. the closed-door is exclusive to my committee, me, and the chair of my defense, and I don’t give a presentation during this.

Everyone congratulated me on my talk and said some nice words about my thesis document. Then I was moved to a Breakout Room while the committee went over the rules of the defense and determined the order in which they would ask me questions. I re-entered the main Zoom room with everyone and then we just went round-robin-style asking questions. (Almost) everyone asked good questions that were actually somewhat fun to discuss.

After approximately an hour of answering questions, I was excused to a Breakout Room for about five minutes. When I was let back in, the committee congratulated me and told me I passed. Huzzah! I now have a terminal degree and I feel quite old.

…So, that was last week. Wow. Time really flies.

The most common question people have asked me in the past week is, “how do you feel?!” Honestly, there are a lot of emotions and I’m probably still processing more. For now, I know I feel accomplishment, happiness, pride, relief, and freedom.

Reflecting on my feelings up to right now as I type, the dominant feelings have been of relief and freedom. I’m relieved that it’s done. I had been frustrated with my research project (what PhD hasn’t?) and had qualms with the fundamental premise of my lab’s research topic. I sincerely hope that other PhD’s don’t experience the latter. I think my sense of freedom stems from speaking up about those qualms, which I decided to do during my closed-door defense.

During the closed-door, one of my committee members asked me, “Do you really think it’s worthwhile to study how muscle development is sensitive to methylmercury?”

To the chagrin of my advisor (and amusement of my committee) I said no.

My advisor became defensive (naturally) which required me to share thoughts I’ve had for the past year and a half on why I think the current focus is unlikely to have a significant impact on public health.

I truly could not believe I said no. However I had some pretty good reasons, given I had perseverated on this for so long. My committee seemed to agree with me, which felt validating. Additionally, my committee asked good questions for the most part; the kind that were broad, thought-provoking, and stimulated some truly good discussion. I wish all of my committee meetings had been more like this!

However, there were some not-so-good questions as well, which was a shame. Whoever said, “there are no bad questions!” was wrong.

Here is how bad questions tend to begin:

I am interested in Thing X and will proceed to talk about it. Oh, I forgot my question. Sorry. *note that Thing X is unrelated to my research*

There were not many bad questions, however I was pretty incredulous that my advisor interrupted me to remind other members of my committee to write a lstter of support for his grant resubmission. The opportunistic nature of this action really just left a bad taste in my mouth. A student’s thesis defense is not the place to remind colleagues to write a letter of support for a grant resubmission… I digress…

Here are some examples of good questions:

I noticed in your talk that X happened during Y. What do you think that meant?

How relevant are these doses and why did you select them?

What is an experiment you could do to test X?

What is one part of your work that you would like to see continued and why?

Also, many of my committee’s questions demonstrated that they had actually read my document. I was worried that no one would have read my document because my advisor told me no one would read it. Thankfully, he was wrong. They read it, and they seemed to have even liked it.

I felt really proud when they congratulated my writing. I enjoy writing and like to think that I’m decent at it. Honestly, after writing 140 pages I better be good at it. The positive reinforcement I received from my committee and defense chair meant the world to me. They used words like “scholarly” and “concise” and others that affirmed my belief in myself and my abilities.

I had one measly edit from the University (to bold my name in my publications) plus one suggestion from my advisor (to rotate one of my figures in my thesis document). But I technically passed with no revisions. Cool.

After I responded to my edits, I uploaded my thesis document to ProQuest so that it can be formally published. I ordered two hard copies too: one for the bookshelf in the Department of Environmental Medicine where all Ph.D. theses have a home, and one for my own bookshelf.

Given I have a manuscript under review, I opted for a year and 3 month embargo period prior to allowing worldwide access to my thesis document. So if anyone is interested in reading my document, please reach out to me directly. Honestly, I would just read the introduction and maybe the discussion if you want to hear me roast my lab’s research premise.

And so that’s a wrap. I’m all done. I’m officially terminated as of August 15 from the University. I begin the next chapter of my career on Monday as a toxicologist. Cheers!

Celebrating with Tim in Durham after my defense

“Arriving at one goal is the starting point to another.” – John Dewey (1859 – 1952)

I have a thesis defense date!

March 30, 2021

It’s official: I have a defense date scheduled for August 10 at 11 am. MARK YOUR CALENDARS, FRIENDS! Also hit me up for that Zoom link. The buildup to this has been pretty stressful, so I am ecstatic that is worked out and I get to leave.

Before August 10, I have to write a thesis — specifically, I turn it in July 6! The average PhD thesis is around 75,000 words. The task is pretty daunting, but I have a strategy to tackle it. Basically, I will write about 15,000 words of introduction, about the same for a discussion, and my two papers will go in between. Older graduate students in my program have called the strategy, “the sandwich method.”

After I write and defend, my next step is a move to Research Triangle Park, North Carolina. My partner has accepted a job at the Environmental Protection Agency, which is AWESOME and I am so freakin’ proud. On my end, I aspire (dream) to become a science journalist that covers environmental health news and toxicology. I have accepted that I might not be able to get there right out of the gate, so I have been casting a wide net with my job applications and career search. I have applied for science communication multimedia fellowships and toxicology consulting and risk assessment positions. Additionally, this week I am meeting with some mentors to *gulp* inquire about post-docs. Ideally the post docs would be at the National Toxicology Program or NIEHS, and have an obvious public-health focus and maybe even value science communication and outreach. Does such a specific post-doc exist?! I have no idea. Hopefully time (and the right contacts) will tell.

At work, my main responsibilities have shifted from laboratory work, writing, and extracurricular activities to mainly writing all day, every day. Honestly, thank GOODNESS because 1) I love to write/edit and 2) I have gotten to the point in my PhD where I want to bang my head against the black Masonite benchtop every other day. Apparently, that level of frustration is a good indication that a student is ready to leave.

Another indication is a publication record.

I published my first first-author manuscript in Toxicology last fall, which is the unwritten base-requirement (in addition to completing coursework and maintaining good academic standing) to graduate from my program. However, my advisor wanted a second first-author publication from me before he would let me go.

At first, I was basically like “heck no this is dumb and I am tired” but in slightly more articulate and professional language, of course. Eventually (and begrudgingly), I acquiesced. While I’m proud of myself for doing it, I must credit a supportive committee member who gave me the tough love I needed to “just write the damn paper and get out.” In a three week span, I pivoted from an obstinate stance against writing the paper at all, to having the first draft completed and sent to my advisor.

That draft has been sitting in his inbox for over a week now, but it’s not productive to dwell…

Anyway, I’m really proud of myself for setting my mind to something and just doing it, even though I very much did not want to. I’m leaving out a lot of details, such as panic attacks and angsty walks to work. In any case, please trust me when I say that my experience with the second paper is pretty emblematic of the grind of a PhD: it can be mentally grueling.

Now would be an opportune time to say something along the lines of, “if it was any other way, everyone would do it.” Approximately 2% of the U.S. population has a PhD, according to Inside Higher Ed. Sure, a small fraction of people in general complete the PhD. Here’s a thought: what if we made it less mentally grueling?! Surely more people would have a PhD. Why is that such a bad thing? I digress. This is definitely a topic for a future post.

Nevertheless, I’m looking forward to joining a tiny nerd-guild of Toxicologists in the very near future.

Quitting the PhD: when you could and why you shouldn’t

November 12, 2020

The challenges that face PhD students in science programs are frequent and often seem insurmountable. When faced with obstacles, is it better to just quit? Spoiler alert — NO! Its not!

Approximately a quarter of graduate students in science or engineering PhD programs in the U.S. will quit within 3 years of matriculation, according to data gathered by the Council of Graduate Schools. Moreover, of the estimated 24,165 graduate students in U.S. natural science doctoral programs, 6,041 will not defend their thesis to earn a PhD.

There are numerous reasons why quitting may be appropriate or inappropriate. Ultimately, the decision to throw in the towel (or not) is extremely personal.

Anecdotally, I have heard that the main reasons for quitting a PhD in the natural sciences include losing interest in the research, wishing to pursue a different passion, and feeling disheartened by academia. These are all totally understandable reasons, and I have felt them too.

There are other struggles, too. Personally, I sometimes think my experimental design is such a mess that my research is not going to help the world in a meaningful way. Every now and then, I consider the possibility that I am only in a PhD program by some fortuitous combination of personal fraud and admissions committee error. Additionally, I often worry that my future career will not require my high level of education. These feelings have certainly been exacerbated by the mental toll of the ongoing COVID19 pandemic, but they had existed before March 2020.

Nevertheless, I won’t quit, and I argue against quitting a PhD in general.

The pandemic will be over, eventually. In the meantime, there is no shame in struggling during these uniquely stressful times, or ever, actually. Change is really hard, and it’s OK to struggle. Pandemic aside, the process of a PhD involves constant changes: moving to a new city, rotating in different laboratories, joining a lab and moving to a new office, forming relationships with your committee members, working through summers, and a revolving door of lab members, to name a few.

While we (usually) can’t control the changes, we can control how we respond to the changes. My thoughts of quitting partially stem from my responses to change: being supportive versus resistant of the changes experienced in academia influence my mood/outlook, which in turn influence how often the thought of quitting occurs.

PPT - Positive Response to Change PowerPoint Presentation, free download -  ID:476522
Personal responses (supportive to resistant) to change (in general) in academia over time

I’m usually in a pretty good mood and want to keep on keeping on, but I have periods of doubt that basically correspond to whenever there is a change. Indeed, I’ve felt the urge to call my advisor and hang up my lab-coat many times over the past few months, but I will not. The doubt will pass. I will defend my thesis sometime in the next two years.

Overcoming this whole mess, and emerging with a PhD is essential for me, and other candidates. Although the degree represents the contribution of new knowledge to the world about a (very specific) problem, the educational process is the most meaningful part. A PhD is an endurance event — basically a marathon. The finish is great, but the race itself is where you learn and grow against a backdrop of constant change.

Sticking it out and holding steady through the “race” is tough. However, like endorphins for a runner, the benefits of a PhD journey increase as you go on. During my PhD so far, I have become educated in much more than Toxicology. I’ve learned how to be kind yet constructive, that PI’s are just people, and that my to-do list is never too long for a run (and other means of self-care!). I want to continue to learn more while I can, so I will stick around. But not too long!

The decision to leave or stay is personal, and I realize I have certain privileges (I don’t have children, I have more free time, etc…) that enable me to make this decision more easily. Nevertheless, should “the benefits of the process” not be a sufficient reason for you to stay, I offer some others:

  1. You worked too hard to get here to quit now.
  2. The effort you have previously put in will amount to a degree that opens doors to subsequent opportunities
  3. You may inspire others to pursue a PhD
  4. By struggling, you have gained experience that you may share with mentees you can guide and help
  5. You CAN do it — anything worth doing is difficult — If it were easy, everyone would have a PhD!
    • Indeed, 2% of the United States population has a PhD., according to US Census Bureau data from 2019.

Although I urge you to stay rather than quit, spending time in a PhD program means you learned something about yourself, and made an informed decision.

“At the center of your being, you have the answer; you know who you are, and you know what you want.” – Lao-Tzu (604 – 531 BC)

Have you thought about quitting? What are your thoughts on the process of getting a PhD? What made it worthwhile for you?

On virtual poster presentations

May 22, 2020 (& June 6, 2020)

As any true academic, I procrastinated something important until the last minute. Someday, This will refer to grants I write or bigger deadlines I must meet, but for this post, it regards a poster competition.

I entered a virtual poster competition that offers CASH prizes for first ($500) and second($250). This is uncharacteristic for a University- sponsored award; the unrestricted money grants me the freedom to spend money on anything I want… probably something very important like rent, food, utility bills, or 1-2 dozen slap-chops.

I implore you to Wach this TV advertisement for commercial excellence…

The stipulations for the award are as follows: 1) The student had a conference cancelled due to COVID19, 2) The poster can be submitted via PDF and 3) the student presents the poster in a .mp4 recording. It seemed easy enough. I figured that it would take a half-hour of my time – tops. Which was good – because I (thought that I) had two hours until it was due.

However – it took me about twice that length. It’s surprisingly nerve-wracking to record yourself giving an academic presentation. It took a few tries to get it right! Below is a blooper from the first of 7 total trials:

Peak derp-level achieved.

While it’s unfortunate that I didn’t get to travel to California to present my research this year at the Society of Toxicology annual meeting, it’s even more unfortunate that I haven’t yet mastered Zoom recordings…🤷🏻‍♀️

I hope you took note of the aforementioned qualifier phrase, “thought that I had.” I was wrong about the May 22 deadline (when I began this post); the presentation and associated files are actually due today! However, I’m glad I finished it then, because today, I was too busy for a last-minute submission scurry. This afternoon, I headed downtown for a few hours of protest, in support the BLM movement with my Rochester community. 🖤✊

Which ostensibly points out…maybe procrastination isn’t a good M.O. to have…

Anyway, I hope y’all enjoy this post & thank you for reading! Wish me luck with the ACTUAL submission! 🙂😂🤷🏻‍♀️

PhDistance | WELCOME

Hi! My name is Ash, and I’m a marathon runner and toxicologist with a Ph.D. A toxicologist is someone who studies the potentially adverse health effects of chemicals.

I started this blog in graduate school to reflect on my experiences and have a space to practice my writing and science communication skills.

I attended the University of Rochester for their toxicology training program, which is housed within the Department of Environmental Medicine. I completed my thesis under the supervision of Dr. Matthew Rand. My thesis work used a fruit fly model to learn about methylmercury toxicity during muscle development. I learned so much and had an overall great experience, but I’m really happy to be done!

When I wasn’t in lab, I was literally running around Rochester. The weather was pretty wild there, given the city’s proximity to the Great Lakes. But, it was usually fun to be out there!

…and other times, it was not:


If it looks like I’m crying, it’s because I am.

During graduate school, I ran 5 marathons and 3 half marathons (see the Races tab). There were injuries, personal records, as well as other highs and lows along the way, and I’m grateful for it all.

I’m currently training for Boston, as you can see by the countdown to the left.

Running continues to keep me sane, provides a “reset” when I feel spun from work, and has led to wonderful friendships. It also gives me those infamous post-run endorphin spikes.

I will continue to recount my post-grad adventures on this blog as I chase after my athletic and career goals.

 Subscribe (email) and follow this blog to keep up as I run towards my goals and away from my problems!